Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139197 | 0.82 | NR1H4 (0.83) | CHRNA7NR1H4MAPTMAPK1MEN1 | |
| SCHEMBL5139199 | 0.82 | NR1H4 (0.83) | CHRNA7NR1H4MAPTMAPK1MEN1 | |
| SCHEMBL661644 | 0.81 | NR1H4 (0.66) | CHRNA7NR1H4MAPTMAPK1MEN1 | |
| SCHEMBL661643 | 0.81 | NR1H4 (0.66) | CHRNA7NR1H4MAPTMAPK1MEN1 | |
| SCHEMBL28906376 | 0.80 | CHRNA7 (0.73) | CHRNA7NR1H4MAPTMAPK1TDP1 | |
| SCHEMBL634386 | 0.79 | CHRNA7 (0.90) | CHRNA7NR1H4MAPTMAPK1KDM4E | |
| SCHEMBL634385 | 0.79 | CHRNA7 (0.90) | CHRNA7NR1H4MAPTMAPK1KDM4E | |
| SCHEMBL19183199 | 0.78 | APP (0.81) | CHRNA7NR1H4MAPTMAPK1TDP1 | |
| SCHEMBL19183197 | 0.78 | APP (0.81) | CHRNA7NR1H4MAPTMAPK1TDP1 | |
| SCHEMBL17220887 | 0.78 | MAPT (0.80) | NR1H4MAPTMAPK1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304513-A | Chalcone derivative with anti-inflammatory activity and synthesis method and application thereof | 湖北科技学院 | 2022-11-08 | — | — | CN | disclosed |