Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906370 | 0.83 | CTSL (0.63) | CHRNA7MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL634386 | 0.82 | CHRNA7 (0.90) | CHRNA7MAPTMEN1MAPK1KMT2A | |
| SCHEMBL634385 | 0.82 | CHRNA7 (0.90) | CHRNA7MAPTMEN1MAPK1KMT2A | |
| SCHEMBL28906359 | 0.81 | AR (0.64) | CHRNA7MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL28906328 | 0.81 | AR (0.63) | CHRNA7MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5082149 | 0.80 | MAPT (1.00) | CHRNA7MAPTMEN1MAPK1KMT2A | |
| SCHEMBL5082144 | 0.80 | MAPT (1.00) | CHRNA7MAPTMEN1MAPK1KMT2A | |
| SCHEMBL28906366 | 0.80 | CHRNA7 (0.59) | CHRNA7MAPTMEN1MAPK1KMT2A | |
| SCHEMBL19183197 | 0.78 | APP (0.81) | CHRNA7MAPTMEN1MAPK1KMT2A | |
| SCHEMBL19183199 | 0.78 | APP (0.81) | CHRNA7MAPTMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304513-A | Chalcone derivative with anti-inflammatory activity and synthesis method and application thereof | 湖北科技学院 | 2022-11-08 | — | — | CN | disclosed |