Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.46 |
| ▸ | TUBB | P07437 | 3/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.46 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6797799 | 0.78 | SLC6A2 (0.47) | SMN1; SMN2MEN1KMT2AADRA2AADRA2B | |
| SCHEMBL7221229 | 0.77 | KMT2A (0.48) | TSHRMEN1KMT2AADRA2AADRA2B | |
| SCHEMBL17681422 | 0.77 | MEN1 (0.48) | MEN1KMT2ASOS1KRASCTSD | |
| SCHEMBL28276198 | 0.76 | CNR2 (0.62) | TSHRSMN1; SMN2MEN1KMT2ATUBB4A | |
| SCHEMBL24953241 | 0.76 | KMT2A (0.56) | TSHRMEN1KMT2AADRA2AADRA2B | |
| SCHEMBL29625688 | 0.76 | KMT2A (0.56) | TSHRMEN1KMT2AADRA2AADRA2B | |
| SCHEMBL4671160 | 0.75 | MAPT (0.42) | MEN1KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL10385726 | 0.75 | SMN1; SMN2 (0.45) | TSHRSMN1; SMN2MEN1KMT2ATUBB4A | |
| SCHEMBL18287920 | 0.75 | MAPT (0.56) | TSHRSMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL477696 | 0.73 | LMNA (0.53) | TSHRMEN1KMT2AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265319-B | Preparation method of di (hetero) arylcarbinol compound | 中国科学院化学研究所 | 2021-02-05 | — | — | CN | disclosed |