Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | SOD1 | P00441 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10330366 | 0.88 | LTA4H (0.46) | LTA4HBACE1HRH3CHEK1CHEK2 | |
| SCHEMBL21507854 | 0.84 | KMT2A (0.48) | HRH3CHEK1CHEK2NR4A2DHODH | |
| SCHEMBL15723552 | 0.84 | MAPK1 (0.58) | — | |
| SCHEMBL13883749 | 0.84 | KDM4E (0.55) | LTA4HCHEK1CHEK2RXRARXRB | |
| SCHEMBL15473215 | 0.83 | KMT2A (0.57) | LTA4HBACE1HRH3HDAC1HDAC2 | |
| SCHEMBL9422520 | 0.83 | LTA4H (0.49) | LTA4HBACE1HRH3HDAC1HDAC2 | |
| SCHEMBL14926626 | 0.82 | LSS (0.59) | LTA4HHRH3HDAC1HDAC2 | |
| SCHEMBL14232127 | 0.82 | LSS (0.59) | LTA4HHRH3HDAC1HDAC2 | |
| SCHEMBL8708778 | 0.82 | KCNA3 (0.58) | LTA4HBACE1HRH3HDAC1HDAC2 | |
| SCHEMBL213738 | 0.82 | KCNA3 (0.64) | LTA4HHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427038-A | Methods of treating nervous system symptoms associated with lysosomal storage diseases | 建新公司 | 2022-12-02 | — | — | CN | disclosed |