Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL263874 | 0.88 | TP53 (0.69) | TP53CA4TSHRSLC7A5CA1 | |
| Lactic Acid SCHEMBL25402793 | 0.88 | TP53 (0.69) | TP53CA4TSHRSLC7A5CA1 | |
| Lactic Acid SCHEMBL28907546 | 0.85 | TP53 (0.65) | TP53CA4TSHRSLC7A5CA2 | |
| Lactic Acid SCHEMBL28026845 | 0.84 | — | — | |
| Lactic Acid SCHEMBL16949962 | 0.84 | TP53 (0.73) | TP53TSHRSLC7A5CA1CA2 | |
| Lactic Acid SCHEMBL11298916 | 0.84 | TP53 (0.73) | TP53TSHRSLC7A5CA1CA2 | |
| Lactic Acid SCHEMBL29020056 | 0.84 | TP53 (0.73) | TP53CA4TSHRSLC7A5CA1 | |
| Lactic Acid SCHEMBL27980401 | 0.84 | TP53 (0.73) | TP53CA4TSHRSLC7A5CA1 | |
| Lactic Acid SCHEMBL2585781 | 0.83 | — | — | |
| Lactic Acid SCHEMBL31230586 | 0.83 | TP53 (0.85) | TP53TSHRSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315446-A | anti-sugar-CD 44 antibodies and uses thereof | GO医疗股份有限公司 | 2022-11-08 | — | — | CN | disclosed |