Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL29389969 | 1.00 | TP53 (0.73) | TP53CA1CA2TSHRCA4 | |
| Lactic Acid SCHEMBL16949962 | 0.93 | TP53 (0.73) | TP53CA1CA2TSHRSLC7A5 | |
| Lactic Acid SCHEMBL27980401 | 0.93 | TP53 (0.73) | TP53CA1CA2TSHRCA4 | |
| Lactic Acid SCHEMBL11298916 | 0.93 | TP53 (0.73) | TP53CA1CA2TSHRSLC7A5 | |
| Lactic Acid SCHEMBL1168924 | 0.90 | TP53 (0.69) | TP53CA1CA2TSHRCA4 | |
| Lactic Acid SCHEMBL4755238 | 0.90 | TP53 (0.69) | TP53CA1CA2TSHRCA4 | |
| Lactic Acid SCHEMBL8024518 | 0.90 | TP53 (0.69) | TP53CA1CA2TSHRCA4 | |
| Lactic Acid SCHEMBL15544221 | 0.90 | TP53 (0.69) | TP53CA1CA2TSHRCA4 | |
| Lactic Acid SCHEMBL264447 | 0.90 | TP53 (0.69) | TP53CA1CA2TSHRCA4 | |
| Lactic Acid SCHEMBL10320997 | 0.88 | TP53 (0.65) | TP53CA1CA2TSHRCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116098991-A | Pharmaceutical compositions containing glucagon conjugates and uses thereof | 派格生物医药(苏州)股份有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-116098991-A | Pharmaceutical compositions containing glucagon conjugates and uses thereof | 派格生物医药(苏州)股份有限公司 | 2023-05-12 | — | — | CN | disclosed |