Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23323086 | 0.87 | MEN1 (0.44) | MEN1KMT2AHRH1CHRM5CHRM3 | |
| SCHEMBL23487072 | 0.83 | MEN1 (0.43) | MEN1KMT2ACHRM5CHRM3CHRM2 | |
| SCHEMBL469013 | 0.81 | MEN1 (0.65) | MEN1KMT2ACHRNB4CHRNA3TACR1 | |
| SCHEMBL29589447 | 0.81 | MEN1 (0.65) | MEN1KMT2ACHRNB4CHRNA3TACR1 | |
| SCHEMBL23323077 | 0.81 | MEN1 (0.65) | MEN1KMT2ACHRNB4CHRNA3TACR1 | |
| SCHEMBL23064531 | 0.81 | MEN1 (0.49) | MEN1KMT2ACHRNB2CHRNA4HTR1A | |
| SCHEMBL31198369 | 0.81 | TACR1 (0.46) | MEN1KMT2ACHRM5CHRM3CHRM2 | |
| SCHEMBL16796794 | 0.81 | TACR1 (0.46) | MEN1KMT2ACHRM5CHRM3CHRM2 | |
| SCHEMBL28500167 | 0.81 | MEN1 (0.49) | MEN1KMT2ACHRNB2CHRNA4HTR1A | |
| SCHEMBL11509481 | 0.79 | HTR1A (0.58) | MEN1KMT2ACHRM5CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |