Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 10/20 | 0.59 |
| ▸ | NPC1 | O15118 | 10/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568774 | 0.86 | KDM4E (0.67) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4108874 | 0.82 | KDR (0.63) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27866684 | 0.82 | NPC1 (0.80) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL240482 | 0.81 | TRPV1 (0.61) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL651159 | 0.81 | KDR (0.74) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL879571 | 0.80 | KDM4E (0.70) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3994400 | 0.80 | NPSR1 (0.71) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14461305 | 0.80 | HDAC1 (0.72) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27617535 | 0.80 | KDR (0.68) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8397726 | 0.79 | TRPV1 (0.58) | KDRKDM4ERAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375037-A | Synthetic method of 3-amino-5-bromoquinoline | 苏州康润医药有限公司 | 2021-02-19 | — | — | CN | claimed |
| CN-112375037-B | Synthetic method of 3-amino-5-bromoquinoline | 苏州康润医药有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-112375037-A | Synthetic method of 3-amino-5-bromoquinoline | 苏州康润医药有限公司 | 2021-02-19 | — | — | CN | disclosed |