Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | KDR | P35968 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 10/20 | 0.67 |
| ▸ | NPC1 | O15118 | 9/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | XBP1 | P17861 | 1/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.65 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27866684 | 0.86 | NPC1 (0.80) | KDM4EKDRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL651159 | 0.85 | KDR (0.74) | KDM4EKDRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13134245 | 0.84 | KDM4E (0.63) | KDM4EKDRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8568774 | 0.84 | KDM4E (0.67) | KDM4EKDRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8562464 | 0.84 | RAB9A (0.72) | KDM4EKDRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3994400 | 0.83 | NPSR1 (0.71) | KDM4EKDRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27617535 | 0.83 | KDR (0.68) | KDM4EKDRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14461305 | 0.83 | HDAC1 (0.72) | KDM4EKDRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL26613449 | 0.83 | MAPK10 (0.57) | KDM4ERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL8115181 | 0.83 | TRPV1 (0.65) | KDM4EKDRRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685392-B | Phenyl-tetrazole oxime derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-119454706-A | Methods of treating KRAS-related cancers | 密歇根大学董事会 | 2025-02-18 | — | — | CN | disclosed |
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |
| US-20230416205-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | TENVIE THERAPEUTICS, INC. | 2023-12-28 | — | — | US | disclosed |
| CN-116997551-A | Synthesis of EGFR modulators | 密歇根大学董事会 | 2023-11-03 | — | — | CN | disclosed |
| EP-4225304-A1 | SYNTHESIS OF EGFR MODULATORS | The Regents of The University of Michigan (US) | 2023-08-16 | — | — | EP | disclosed |
| CN-109265451-B | Butyrylcholinesterase selective inhibitor and preparation method and application thereof | 中国药科大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-114685392-A | Phenyl-tetrazole oxime derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2022-07-01 | — | — | CN | disclosed |
| WO-2022081514-A1 | SYNTHESIS OF EGFR MODULATORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-04-21 | — | — | WO | disclosed |
| US-8394828-B2 | Quinoline-derived amide modulators of vanilloid VR1 receptor | JANSSEN PHARMACEUTICA, NV (BE) | 2013-03-12 | — | — | US | disclosed |
| EP-1214326-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001018006-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| CN-1169986-A | 2.9-diamino-and 2-amino-8-carbamoyl-4-hydroxy-aldanoic acid amide derivatives | CIBA GEIGY AG (CH) | 1998-01-14 | — | — | CN | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |
| EP-0276842-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5035993-A | Quaternary ammonium salt nucleating agent | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-30 | — | — | US | disclosed |
| US-4877723-A | EMULSION LAYER CONTAINING AN ALKYNYL-SUBSTITUTED HETEROCYCLIC QUATERNARY AMMONIUM SALT; DIRECT POSITIVES; REVERSAL | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| US-4859579-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-22 | — | — | US | disclosed |
| US-4828973-A | DIRECT POSITIVES WITH REVERSAL PROPERTIES | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416205-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NLRP3, NLRP1, NOD1 | KDM4E 3822/4885KDR 4430/4885RAB9A 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.