Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28908174 | 0.94 | SMN1; SMN2 (0.38) | MAPTTDP1CA1CA2POLB | |
| SCHEMBL28908166 | 0.93 | CA1 (0.37) | HTTMAPTKDM4ENPSR1TDP1 | |
| SCHEMBL28960548 | 0.90 | CA1 (0.34) | HTTMAPTKDM4ETDP1CA1 | |
| SCHEMBL28908216 | 0.89 | RXFP1 (0.34) | HTTKDM4ECA1CA2POLB | |
| SCHEMBL28908171 | 0.89 | POLB (0.35) | MAPTCA1CA2POLBNPC1 | |
| SCHEMBL28908203 | 0.89 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL28960551 | 0.89 | ADCY8 (0.33) | HTTKDM4ECA1CA2POLB | |
| SCHEMBL1795743 | 0.89 | CA1 (0.36) | HTTMAPTKDM4ETDP1CA1 | |
| SCHEMBL740200 | 0.89 | CA1 (0.40) | KDM4ECA1CA2NPC1RAB9A | |
| SCHEMBL738508 | 0.89 | CA1 (0.36) | MAPTKDM4ECA1CA2ORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380762-A | Isoxazoline hydrazide derivative and preparation method and application thereof | 贵州大学 | 2022-04-22 | — | — | CN | disclosed |