Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9917383 | 0.82 | HRH3 (0.51) | ALDH1A1HRH3MAPK1CYP1A2CHRM2 | |
| SCHEMBL23480661 | 0.79 | HRH3 (0.49) | ALDH1A1HRH3MAPK1CYP1A2CHRM2 | |
| SCHEMBL21093848 | 0.79 | HRH3 (0.49) | ALDH1A1HRH3MAPK1CYP1A2CHRM2 | |
| SCHEMBL24728751 | 0.79 | HRH3 (0.49) | ALDH1A1HRH3MAPK1CYP1A2CHRM2 | |
| SCHEMBL21733612 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HRH3MAPK1CYP1A2CHRM2 | |
| SCHEMBL10100370 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HRH3MAPK1CYP1A2CHRM2 | |
| SCHEMBL24084211 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HRH3MAPK1CYP1A2CHRM2 | |
| SCHEMBL26581778 | 0.77 | HRH3 (0.46) | ALDH1A1HRH3MAPK1CYP1A2CHRM2 | |
| SCHEMBL20328708 | 0.77 | MAPK1 (0.46) | ALDH1A1HRH3MAPK1CYP1A2CHRM2 | |
| SCHEMBL21118910 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HRH3MAPK1CYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067433-A1 | COMPOUND TARGETING INTEGRIN AND USE THEREOF IN RNAI AGENT | 云合智药（苏州）生物科技有限公司 | 2025-04-03 | — | — | WO | disclosed |
| WO-2025040139-A1 | RNAI AGENT FOR INHIBITING DIACYLGLYCEROL-O-ACYLTRANSFERASE 2 EXPRESSION, AND APPLICATION THEREOF | 云合智药（苏州）生物科技有限公司 | 2025-02-27 | — | — | WO | disclosed |
| WO-2025016294-A1 | RNAI AGENT FOR INHIBITING EXPRESSION OF KETOHEXOKINASE AND USE THEREOF | 云合智药（苏州）生物科技有限公司 | 2025-01-23 | — | — | WO | disclosed |
| CN-118804921-A | Conjugate, ligand unit and use thereof | 云合智药（苏州）生物科技有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-118667811-A | Ketohexokinase (KHK) iRNA compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2024-09-20 | — | — | CN | disclosed |
| WO-2024152775-A1 | CONJUGATE, LIGAND UNIT AND USE THEREOF | 云合智药（苏州）生物科技有限公司 | 2024-07-25 | — | — | WO | disclosed |
| CN-112424355-A | Ketohexokinase (KHK) iRNA compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2021-02-26 | — | — | CN | disclosed |