Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28785562 | 0.83 | KDM4E (0.41) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL28512651 | 0.81 | KDM4E (0.40) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21531488 | 0.76 | KDM4E (0.36) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7098395 | 0.75 | MAPT (0.38) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9935511 | 0.72 | KDM4E (0.36) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21989833 | 0.72 | KDM4E (0.44) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| Dibenzo[B,F]Oxepine SCHEMBL1650179 | 0.69 | MEN1 (0.64) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9933267 | 0.68 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9934212 | 0.68 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8685834 | 0.66 | ALOX15 (0.37) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728918-B | RIP1 inhibitory compounds and methods of making and using the same | 里格尔药品股份有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-112368278-B | RIP1 inhibitory compounds and methods of making and using the same | 里格尔药品股份有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-114761398-A | Heterocyclic RIP1 kinase inhibitors | 里格尔药品股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114728918-A | RIP1 inhibiting compounds and methods of making and using the same | 里格尔药品股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114728958-A | RIP1 inhibiting compounds and methods of making and using the same | 里格尔药品股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-112368278-A | RIP1 inhibiting compounds and methods of making and using the same | 里格尔药品股份有限公司 | 2021-02-12 | — | — | CN | disclosed |