SCHEMBL28908646

SCHEMBL28908646

CC(C)(C)[Si](C)(C)OCCCC1CCO1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.44
DUT P33316 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28908835 0.89 EPHX1 (0.38) EPHX1
SCHEMBL2245757 0.85 ALDH1A1 (0.41) DUT
SCHEMBL592816 0.85 ALDH1A1 (0.41) DUT
SCHEMBL2223898 0.85 ALDH1A1 (0.41) DUT
SCHEMBL591257 0.80 ALDH1A1 (0.44) DUT
SCHEMBL336309 0.79 ALDH1A1 (0.47) EPHX1DUT
SCHEMBL335223 0.79 ALDH1A1 (0.47) EPHX1DUT
SCHEMBL30209271 0.77 ALDH1A1 (0.34) EPHX1
SCHEMBL14513917 0.77 SLC6A4 (0.35) EPHX1DUT
SCHEMBL14513913 0.77 SLC6A4 (0.35) EPHX1DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115298176-A Compounds and their use in the treatment of bacterial infections 豪夫迈·罗氏有限公司 2022-11-04 CN disclosed