Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Dextrocarnitine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.79 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levocarnitine SCHEMBL374454 | 0.91 | MAPT (0.95) | MAPTSLC22A16SLC22A6LMNASMN1; SMN2 | |
| Dextrocarnitine SCHEMBL1069009 | 0.91 | MAPT (0.95) | MAPTSLC22A16SLC22A6LMNASMN1; SMN2 | |
| Levocarnitine SCHEMBL13034193 | 0.91 | MAPT (0.95) | MAPTSLC22A16SLC22A6LMNASMN1; SMN2 | |
| Dextrocarnitine SCHEMBL10496258 | 0.89 | MAPT (0.91) | MAPTSLC22A16SLC22A6LMNASMN1; SMN2 | |
| Dextrocarnitine SCHEMBL19896368 | 0.89 | MAPT (0.91) | MAPTSLC22A16SLC22A6LMNASMN1; SMN2 | |
| Levocarnitine SCHEMBL23045915 | 0.89 | MAPT (0.91) | MAPTSLC22A16SLC22A6LMNASMN1; SMN2 | |
| Levocarnitine SCHEMBL3007086 | 0.89 | MAPT (0.91) | MAPTSLC22A16SLC22A6LMNASMN1; SMN2 | |
| Dextrocarnitine SCHEMBL1820591 | 0.89 | MAPT (0.91) | MAPTSLC22A16SLC22A6LMNASMN1; SMN2 | |
| Dextrocarnitine SCHEMBL20447744 | 0.89 | MAPT (0.91) | MAPTSLC22A16SLC22A6LMNASMN1; SMN2 | |
| Dextrocarnitine SCHEMBL23045916 | 0.89 | MAPT (0.91) | MAPTSLC22A16SLC22A6LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115317398-B | Ionic liquid collagen preparation and preparation method and application thereof | 广州樊文花化妆品有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-115317398-A | Ionic liquid collagen preparation and preparation method and application thereof | 广州樊文花化妆品有限公司 | 2022-11-11 | — | — | CN | disclosed |