Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | MTTP | P55157 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007107 | 1.00 | MAPT (0.35) | MAPTPOLBROCK2ROCK1CFTR | |
| SCHEMBL25687257 | 1.00 | MAPT (0.35) | MAPTPOLBROCK2ROCK1CFTR | |
| SCHEMBL25275834 | 0.94 | CFTR (0.36) | MAPTROCK2ROCK1CFTRCYP2C9 | |
| SCHEMBL25687253 | 0.94 | CFTR (0.36) | MAPTROCK2ROCK1CFTRCYP2C9 | |
| SCHEMBL30006992 | 0.91 | CTSA (0.35) | MAPTROCK2ROCK1CYP2C9MAPK14 | |
| SCHEMBL23958805 | 0.91 | CTSA (0.35) | MAPTROCK2ROCK1CYP2C9MAPK14 | |
| SCHEMBL23958639 | 0.91 | CTSA (0.35) | MAPTROCK2ROCK1CYP2C9MAPK14 | |
| SCHEMBL23958772 | 0.90 | MAPT (0.35) | MAPTPOLBROCK2ROCK1CFTR | |
| SCHEMBL30007276 | 0.90 | MAPT (0.35) | MAPTPOLBROCK2ROCK1CFTR | |
| SCHEMBL25687358 | 0.90 | MAPT (0.35) | MAPTPOLBROCK2ROCK1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |