Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CFTR | P13569 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25687358 | 1.00 | MAPT (0.35) | MAPTCFTRPOLBROCK2ROCK1 | |
| SCHEMBL23958772 | 1.00 | MAPT (0.35) | MAPTCFTRPOLBROCK2ROCK1 | |
| SCHEMBL23958706 | 0.94 | CFTR (0.36) | MAPTCFTRPOLBROCK2ROCK1 | |
| SCHEMBL30007924 | 0.94 | CFTR (0.36) | MAPTCFTRPOLBROCK2ROCK1 | |
| SCHEMBL23958644 | 0.94 | CFTR (0.36) | MAPTCFTRPOLBROCK2ROCK1 | |
| SCHEMBL25687411 | 0.94 | CFTR (0.36) | MAPTCFTRPOLBROCK2ROCK1 | |
| SCHEMBL28909201 | 0.92 | CNR1 (0.37) | MAPTCFTRROCK2ROCK1TP53 | |
| SCHEMBL30007246 | 0.92 | CNR1 (0.37) | MAPTCFTRROCK2ROCK1TP53 | |
| SCHEMBL25687416 | 0.92 | CNR1 (0.37) | MAPTCFTRROCK2ROCK1TP53 | |
| SCHEMBL25232511 | 0.92 | CFTR (0.31) | CFTRCYP2C9MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |