Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | FPR2 | P25090 | 3/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958758 | 0.76 | ALDH1A1 (0.46) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL10284484 | 0.76 | SCN9A (0.60) | SCN9AFPR2PLA2G2A | |
| SCHEMBL23930033 | 0.75 | NPC1 (0.44) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL19207313 | 0.75 | NPC1 (0.51) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL16533700 | 0.75 | NPC1 (0.51) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL30007819 | 0.75 | NPC1 (0.51) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL28909202 | 0.75 | SCN9A (0.34) | RAB9ASMN1; SMN2SCN9AADORA3ADORA2A | |
| SCHEMBL30211297 | 0.74 | ALDH1A1 (0.43) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL805895 | 0.71 | SCN9A (0.64) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL25241472 | 0.70 | NPC1 (0.51) | NPC1CASP3RAB9ASMN1; SMN2SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |