Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC2R | Q01718 | 15/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540331 | 1.00 | MC2R (0.63) | MC2RMEN1NPC1MAPTKMT2A | |
| SCHEMBL28539410 | 0.93 | MC2R (0.56) | MC2RHCRTR1HCRTR2 | |
| SCHEMBL28909247 | 0.92 | MC2R (0.57) | MC2RHCRTR1HCRTR2 | |
| SCHEMBL28537151 | 0.92 | MC2R (0.63) | MC2RMEN1NPC1MAPTKMT2A | |
| SCHEMBL21700694 | 0.92 | MC2R (0.76) | MC2RMEN1NPC1MAPTKMT2A | |
| SCHEMBL21700744 | 0.92 | MC2R (0.76) | MC2RMEN1NPC1MAPTKMT2A | |
| SCHEMBL28536533 | 0.91 | MC2R (0.63) | MC2RMEN1NPC1MAPTKMT2A | |
| SCHEMBL28546682 | 0.91 | MC2R (0.66) | MC2RMEN1NPC1MAPTKMT2A | |
| SCHEMBL28910489 | 0.91 | MC2R (0.60) | MC2RHCRTR1HCRTR2 | |
| SCHEMBL28540340 | 0.90 | MC2R (0.57) | MC2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533904-A | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-112533904-A | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2021-03-19 | — | — | CN | disclosed |