Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22291496 | 1.00 | CHRM2 (0.42) | CHRM2HDAC1HDAC2HDAC6CA14 | |
| SCHEMBL2722798 | 1.00 | CHRM2 (0.42) | CHRM2HDAC1HDAC2HDAC6CA14 | |
| SCHEMBL18391125 | 1.00 | CHRM2 (0.42) | CHRM2HDAC1HDAC2HDAC6CA14 | |
| SCHEMBL1654128 | 0.98 | CA14 (0.40) | CHRM2HDAC1HDAC2HDAC6CA14 | |
| SCHEMBL55404 | 0.93 | HDAC6 (0.38) | CHRM2HDAC1HDAC2HDAC6CA14 | |
| SCHEMBL17770771 | 0.92 | CA14 (0.49) | CHRM2HDAC1HDAC2HDAC6CA14 | |
| Hydrochloric Acid SCHEMBL28028259 | 0.91 | HDAC6 (0.37) | CHRM2HDAC1HDAC2HDAC6CA14 | |
| SCHEMBL15284921 | 0.89 | CA14 (0.40) | HDAC6CA14PAOXCTSKLMNA | |
| SCHEMBL23728825 | 0.86 | CHRM2 (0.39) | CHRM2HDAC1HDAC2HDAC6CA14 | |
| SCHEMBL25720861 | 0.85 | ALDH1A1 (0.42) | CHRM2HDAC1HDAC2HDAC6CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167105-A1 | BCL-2 PROTEIN INHIBITORS | RECURIUM IP HOLDINGS, LLC | 2023-06-01 | — | — | US | disclosed |
| EP-4107152-A1 | BCL-2 PROTEIN INHIBITORS | Recurium IP Holdings, LLC (US) | 2022-12-28 | — | — | EP | disclosed |
| CN-115461335-A | BCL-2 protein inhibitors | 里科瑞尔姆IP控股有限责任公司 | 2022-12-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167105-A1 | BCL-2 PROTEIN INHIBITORS | BCL2, BCL2L1, BCL2L2 | CHRM2 4881/4885HDAC1 409/4885HDAC2 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.