Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 10/20 | 0.68 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.68 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.49 |
| ▸ | PDE6D | O43924 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20442798 | 0.98 | DDB1 (0.69) | DDB1CRBNGPR119PDE6DSTAT3 | |
| SCHEMBL29614567 | 0.94 | CRBN (0.71) | DDB1CRBNGPR119STAT3GSPT1 | |
| SCHEMBL24420973 | 0.94 | CRBN (0.71) | DDB1CRBNGPR119STAT3GSPT1 | |
| SCHEMBL30526101 | 0.94 | CRBN (0.61) | DDB1CRBNGPR119PDE6DSTAT3 | |
| SCHEMBL31240354 | 0.94 | CRBN (0.61) | DDB1CRBNGPR119PDE6DSTAT3 | |
| SCHEMBL22276597 | 0.92 | CRBN (0.66) | DDB1CRBNSTAT3GSPT1EGFR | |
| SCHEMBL30058728 | 0.89 | DDB1 (0.66) | DDB1CRBNGPR119PDE6DSTAT3 | |
| SCHEMBL23705558 | 0.89 | DDB1 (0.66) | DDB1CRBNGPR119PDE6DSTAT3 | |
| SCHEMBL30805376 | 0.89 | DDB1 (0.70) | DDB1CRBNGPR119STAT3 | |
| SCHEMBL31405232 | 0.88 | CRBN (0.61) | DDB1CRBNGPR119STAT3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461335-A | BCL-2 protein inhibitors | 里科瑞尔姆IP控股有限责任公司 | 2022-12-09 | — | — | CN | disclosed |