SCHEMBL30058728

SCHEMBL30058728

CC(C)(C)OC(=O)N1CC2(CCN(CCCNc3ccc4c(c3)C(=O)N(C3CCC(=O)NC3=O)C4=O)CC2)C1

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 11/20 0.66
▸ CRBN Q96SW2 11/20 0.66
▸ STAT3 P40763 1/20 0.46
▸ GSPT1 P15170 3/20 0.46
▸ GPR119 Q8TDV5 3/20 0.45
▸ EGFR P00533 1/20 0.44
▸ PDE6D O43924 1/20 0.44
▸ GRAMD1A Q96CP6 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23705558 1.00 DDB1 (0.66) DDB1CRBNSTAT3GSPT1GPR119
SCHEMBL20442798 0.92 DDB1 (0.69) DDB1CRBNSTAT3GSPT1GPR119
SCHEMBL28909815 0.89 DDB1 (0.68) DDB1CRBNSTAT3GSPT1GPR119
SCHEMBL22276652 0.88 DDB1 (0.65) DDB1CRBNSTAT3GSPT1GPR119
SCHEMBL21070717 0.87 DDB1 (0.65) DDB1CRBNSTAT3GSPT1EGFR
SCHEMBL29614567 0.87 CRBN (0.71) DDB1CRBNSTAT3GSPT1GPR119
SCHEMBL24420973 0.87 CRBN (0.71) DDB1CRBNSTAT3GSPT1GPR119
SCHEMBL22276597 0.85 CRBN (0.66) DDB1CRBNSTAT3GSPT1EGFR
SCHEMBL30526101 0.85 CRBN (0.61) DDB1CRBNSTAT3GSPT1GPR119
SCHEMBL31240354 0.85 CRBN (0.61) DDB1CRBNSTAT3GSPT1GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115335373-B Compounds and uses thereof 福宏治疗公司 2025-05-20 — — CN disclosed
EP-4097096-A2 COMPOUNDS AND USES THEREOF Foghorn Therapeutics Inc. (US) 2022-12-07 — — EP disclosed
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