Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SDHB | P21912 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985711 | 0.84 | KDM4E (0.47) | KDM4EHSD17B10MAPK1TDP1TSHR | |
| SCHEMBL19805905 | 0.83 | SDHB (0.54) | KDM4EHSD17B10MAPK1TDP1TSHR | |
| SCHEMBL29976249 | 0.83 | SDHB (0.54) | KDM4EHSD17B10MAPK1TDP1TSHR | |
| SCHEMBL23897438 | 0.83 | KDM4E (0.46) | KDM4EHSD17B10MAPK1TDP1TSHR | |
| SCHEMBL19805635 | 0.81 | SDHB (0.59) | KDM4EHSD17B10MAPK1TDP1TSHR | |
| SCHEMBL29976621 | 0.81 | SDHB (0.59) | KDM4EHSD17B10MAPK1TDP1TSHR | |
| SCHEMBL19805732 | 0.80 | TP53 (0.49) | KDM4EHSD17B10MAPK1TDP1TSHR | |
| SCHEMBL29976339 | 0.80 | TP53 (0.49) | KDM4EHSD17B10MAPK1TDP1TSHR | |
| SCHEMBL29977092 | 0.79 | ADORA2A (0.53) | KDM4EHSD17B10MAPK1TDP1TSHR | |
| SCHEMBL19805742 | 0.79 | ADORA2A (0.53) | KDM4EHSD17B10MAPK1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |