SCHEMBL28910795

SCHEMBL28910795

C=CC(=O)OCCC1CC(=O)NC1=O

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.42
ALDH1A1 P00352 4/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
CYP3A4 P08684 2/20 0.42
HSD17B10 Q99714 1/20 0.42
THRB P10828 2/20 0.40
HPGD P15428 1/20 0.39
GLA P06280 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.32
MAPK1 P28482 1/20 0.32
MAP3K14 Q99558 1/20 0.32
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31396751 0.86 TSHR (0.35) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28042911 0.82 TSHR (0.35) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Ethyl Ester SCHEMBL31065432 0.78 ALDH1A1 (0.42) TSHRALDH1A1CYP3A4THRBHPGD
Acrylic Acid Ethyl Ester SCHEMBL31065421 0.78 ALDH1A1 (0.42) TSHRALDH1A1CYP3A4THRBHPGD
Acrylic Acid SCHEMBL31065413 0.73 ALDH1A1 (0.35) ALDH1A1HSD17B10HPGDGLAMAP3K14
Acrylic Acid SCHEMBL31065399 0.71 GLA (0.35) GLAMAP3K14LMNADDB1CRBN
SCHEMBL28479332 0.71 MAP3K14 (0.50) GLAMAP3K14LMNAMAPTPKM
SCHEMBL14341640 0.71 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid SCHEMBL31065410 0.71 ALDH1A1 (0.39) ALDH1A1HPGDGLALMNAMAPT
SCHEMBL309593 0.70 MAP3K14 (0.35) MAP3K14DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240350970-A1 SEPARATION FUNCTIONAL LAYER, SEPARATION MEMBRANE, AND METHOD FOR MANUFACTURING SEPARATION FUNCTIONAL LAYER NITTO DENKO CORPORATION (JP) 2024-10-24 US disclosed
EP-4400204-A1 SEPARATION FUNCTION LAYER, SEPARATION MEMBRANE, AND PRODUCTION METHOD FOR SEPARATION FUNCTION LAYER NITTO DENKO CORPORATION (JP) 2024-07-17 EP disclosed
WO-2023119879-A1 SEPARATION FUNCTION LAYER, SEPARATION MEMBRANE, AND MEMBRANE SEPARATION METHOD 日東電工株式会社 2023-06-29 WO disclosed
WO-2023032744-A1 SEPARATION FUNCTION LAYER, SEPARATION MEMBRANE, AND PRODUCTION METHOD FOR SEPARATION FUNCTION LAYER 日東電工株式会社 2023-03-09 WO disclosed
WO-2022185891-A1 SEPARATION MEMBRANE 日東電工株式会社 2022-09-09 WO disclosed
CN-112639026-A Method for producing structure containing ionic liquid, and structure containing ionic liquid 日东电工株式会社 2021-04-09 CN disclosed