Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CPN1 | P15169 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28445931 | 1.00 | KMT2A (0.48) | KMT2ACPB2HTR2ACPN1CPB1 | |
| SCHEMBL28911003 | 1.00 | KMT2A (0.48) | KMT2ACPB2HTR2ACPN1CPB1 | |
| SCHEMBL3781893 | 0.84 | HRH1 (0.59) | CPB2HTR2ACPN1CPB1HRH1 | |
| SCHEMBL961952 | 0.83 | KMT2A (0.51) | KMT2ACPB2CPN1ALOX5CYP2C19 | |
| SCHEMBL27400979 | 0.83 | POLB (0.49) | KMT2ACPB2HTR2ACPN1CPB1 | |
| SCHEMBL1966272 | 0.83 | KMT2A (0.55) | KMT2ACPB2CPN1ALOX5CYP2C19 | |
| SCHEMBL5370872 | 0.82 | KMT2A (0.53) | KMT2ACPB2HTR2ACPN1ALOX5 | |
| SCHEMBL9859821 | 0.80 | LMNA (0.48) | KMT2APOLBMEN1 | |
| SCHEMBL12500531 | 0.80 | LMNA (0.48) | KMT2APOLBMEN1 | |
| SCHEMBL30179988 | 0.79 | KMT2A (0.48) | KMT2ACPB2HTR2ACPN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111592467-B | Nilaparib intermediate, preparation method and application thereof, and synthetic method of nilapab | 宁波人健化学制药有限公司 | 2022-12-13 | — | — | CN | disclosed |