Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12297713 | 0.93 | RAB9A (0.75) | MAPTRAB9ANPC1GAAMAPK1 | |
| SCHEMBL28911454 | 0.82 | MAPT (0.60) | MAPTRAB9ANPC1GAAMAPK1 | |
| SCHEMBL28911463 | 0.82 | RAB9A (0.60) | MAPTRAB9ANPC1GAAMAPK1 | |
| SCHEMBL28911500 | 0.81 | MAPT (0.59) | MAPTRAB9ANPC1GAAMAPK1 | |
| SCHEMBL29107310 | 0.81 | MAPT (0.59) | MAPTRAB9ANPC1GAAMAPK1 | |
| SCHEMBL30118260 | 0.81 | MAPT (0.59) | MAPTRAB9ANPC1GAAMAPK1 | |
| SCHEMBL25329191 | 0.81 | RAB9A (0.59) | MAPTRAB9ANPC1GAAMAPK1 | |
| SCHEMBL28911475 | 0.80 | MAPT (0.76) | MAPTRAB9ANPC1GAAMAPK1 | |
| SCHEMBL28911493 | 0.80 | RAB9A (0.57) | MAPTRAB9ANPC1GAAMAPK1 | |
| SCHEMBL28961182 | 0.80 | RAB9A (0.57) | MAPTRAB9ANPC1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448915-A | SIRT5 inhibitor and preparation method and application thereof | 广西师范大学 | 2022-12-09 | — | — | CN | claimed |
| CN-115448915-A | SIRT5 inhibitor and preparation method and application thereof | 广西师范大学 | 2022-12-09 | — | — | CN | disclosed |