Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.49 |
| ▸ | GSK3A | P49840 | 19/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28911764 | 0.91 | GSK3B (0.49) | GSK3BGSK3AJAK2PIM1CDK2 | |
| SCHEMBL28911723 | 0.90 | GSK3B (0.50) | GSK3BGSK3AJAK2PIM1CDK2 | |
| SCHEMBL28911699 | 0.87 | GSK3A (0.51) | GSK3BGSK3AJAK2PIM1CDK2 | |
| SCHEMBL28911746 | 0.86 | GSK3A (0.52) | GSK3BGSK3AJAK2PIM1CDK2 | |
| SCHEMBL28911786 | 0.85 | GSK3A (0.52) | GSK3BGSK3A | |
| SCHEMBL20205175 | 0.85 | GSK3B (0.69) | GSK3BGSK3AJAK2PIM1CDK2 | |
| SCHEMBL28911739 | 0.84 | GSK3B (0.46) | GSK3BGSK3AJAK2PIM1CDK2 | |
| SCHEMBL28911741 | 0.83 | GSK3B (0.52) | GSK3BGSK3AJAK2PIM1CDK2 | |
| SCHEMBL28911727 | 0.82 | GSK3A (0.61) | GSK3BGSK3AJAK2PIM1CDK2 | |
| SCHEMBL28911767 | 0.82 | GSK3A (0.69) | GSK3BGSK3AJAK2PIM1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110545817-B | GSK-3 inhibitors | 百时美施贵宝公司 | 2022-11-15 | — | — | CN | disclosed |