Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 19/20 | 0.52 |
| ▸ | GSK3B | P49841 | 19/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28911723 | 0.91 | GSK3B (0.50) | GSK3AGSK3B | |
| SCHEMBL28911739 | 0.89 | GSK3B (0.46) | GSK3AGSK3B | |
| SCHEMBL28911764 | 0.88 | GSK3B (0.49) | GSK3AGSK3B | |
| SCHEMBL28911767 | 0.86 | GSK3A (0.69) | GSK3AGSK3B | |
| SCHEMBL28911699 | 0.86 | GSK3A (0.51) | GSK3AGSK3B | |
| SCHEMBL28911697 | 0.85 | GSK3B (0.49) | GSK3AGSK3B | |
| SCHEMBL20205046 | 0.85 | GSK3B (0.74) | GSK3AGSK3B | |
| SCHEMBL28911746 | 0.85 | GSK3A (0.52) | GSK3AGSK3B | |
| SCHEMBL28911783 | 0.83 | GSK3A (0.56) | GSK3AGSK3B | |
| SCHEMBL28911741 | 0.82 | GSK3B (0.52) | GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110545817-B | GSK-3 inhibitors | 百时美施贵宝公司 | 2022-11-15 | — | — | CN | disclosed |