Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 7/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19518274 | 0.76 | BRD4 (0.49) | BRD4CREBBPS1PR5S1PR1KCNH2 | |
| SCHEMBL28566657 | 0.69 | CREBBP (0.62) | BRD4CREBBPS1PR5S1PR1KCNH2 | |
| SCHEMBL22368833 | 0.68 | CREBBP (0.64) | BRD4CREBBPS1PR5S1PR1KCNH2 | |
| SCHEMBL22368924 | 0.68 | CREBBP (0.64) | BRD4CREBBPS1PR5S1PR1KCNH2 | |
| SCHEMBL22369023 | 0.65 | BRD4 (0.52) | BRD4CREBBPS1PR5S1PR1KCNH2 | |
| SCHEMBL28555707 | 0.65 | BRD4 (0.62) | BRD4CREBBPS1PR5S1PR1KCNH2 | |
| SCHEMBL17673118 | 0.64 | CREBBP (1.00) | BRD4CREBBP | |
| SCHEMBL28311918 | 0.64 | HRH3 (0.53) | — | |
| SCHEMBL17673303 | 0.64 | CREBBP (1.00) | BRD4CREBBP | |
| SCHEMBL1299481 | 0.63 | IGLV6-57 (0.47) | BRD4CREBBPS1PR5S1PR1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108512-B | Therapeutic compounds and uses thereof | 基因泰克公司 | 2021-05-04 | — | — | CN | disclosed |