Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 5/20 | 0.62 |
| ▸ | BRD4 | O60885 | 4/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22368680 | 0.82 | CREBBP (0.63) | CREBBPBRD4KCNH2SCN3AIGLV6-57 | |
| SCHEMBL28555707 | 0.81 | BRD4 (0.62) | CREBBPBRD4KCNH2SCN3AIGLV6-57 | |
| SCHEMBL17673118 | 0.77 | CREBBP (1.00) | CREBBPBRD4 | |
| SCHEMBL17673303 | 0.77 | CREBBP (1.00) | CREBBPBRD4 | |
| SCHEMBL29576846 | 0.75 | CREBBP (0.47) | CREBBPBRD4 | |
| SCHEMBL22368830 | 0.73 | CREBBP (0.72) | CREBBPBRD4KCNH2SCN3AIGLV6-57 | |
| SCHEMBL28937477 | 0.71 | ADRA2A (0.36) | CREBBPBRD4ALOX5 | |
| SCHEMBL28911998 | 0.69 | BRD4 (0.47) | CREBBPBRD4KCNH2SCN3AIGLV6-57 | |
| SCHEMBL22368922 | 0.67 | CREBBP (0.72) | CREBBPBRD4KCNH2SCN3AIGLV6-57 | |
| SCHEMBL27898293 | 0.65 | BRD4 (0.47) | CREBBPBRD4KCNH2SCN3AIGLV6-57 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108512-B | Therapeutic compounds and uses thereof | 基因泰克公司 | 2021-05-04 | — | — | CN | disclosed |