Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28912156 | 1.00 | LDHA (0.51) | LDHASLC6A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL28558904 | 0.80 | LDHA (0.49) | LDHASLC6A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL28558905 | 0.80 | LDHA (0.49) | LDHASLC6A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL28549063 | 0.80 | LDHA (0.46) | LDHAACACBPOLBHTT | |
| SCHEMBL28549393 | 0.77 | LDHA (0.56) | LDHASLC6A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL28562541 | 0.76 | LDHA (0.54) | LDHASLC6A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL28570428 | 0.75 | LDHA (0.53) | LDHASLC6A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL28562317 | 0.74 | LDHA (0.49) | LDHASLC6A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL28562316 | 0.74 | LDHA (0.49) | LDHASLC6A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL28912151 | 0.73 | LDHA (0.51) | LDHASLC6A4CYP2C19CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848962-B | Urea derivative or pharmacologically acceptable salt thereof | 杏林制药株式会社 | 2021-04-09 | — | — | CN | disclosed |