Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21058321 | 1.00 | MAPT (0.34) | MAPTGAATSHRATR | |
| SCHEMBL21958284 | 0.86 | MAPT (0.32) | MAPTGAA | |
| SCHEMBL28562895 | 0.86 | MAPT (0.32) | MAPTGAA | |
| SCHEMBL21986932 | 0.86 | MAPT (0.32) | MAPTGAA | |
| SCHEMBL17925845 | 0.86 | MAPT (0.32) | MAPTGAA | |
| SCHEMBL21058323 | 0.86 | MAPT (0.32) | MAPTGAA | |
| SCHEMBL21058306 | 0.84 | TSHR (0.33) | MAPTTSHR | |
| SCHEMBL19632326 | 0.82 | GPR119 (0.38) | — | |
| SCHEMBL21058315 | 0.82 | GPR119 (0.38) | — | |
| SCHEMBL21058304 | 0.81 | MAPT (0.31) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153682-B | Novel pyrazine compounds with oxygen, sulfur and nitrogen linkers for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2021-05-25 | — | — | CN | disclosed |