Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18343409 | 0.86 | KCNK3 (0.61) | ROCK2ROCK1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL257797 | 0.85 | CA1 (0.68) | RAB9ASMN1; SMN2NPC1CA1CA2 | |
| SCHEMBL29517828 | 0.83 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1TP53LMNA | |
| SCHEMBL441557 | 0.83 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1TP53LMNA | |
| SCHEMBL8260460 | 0.80 | CA1 (0.50) | ROCK2ROCK1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14165417 | 0.80 | CA1 (0.68) | RAB9ASMN1; SMN2NPC1CA1CA2 | |
| SCHEMBL4771766 | 0.79 | CA1 (0.49) | ROCK2ROCK1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15481246 | 0.79 | CA1 (0.70) | RAB9ANPC1TP53CA1CA2 | |
| SCHEMBL1331266 | 0.79 | CA1 (0.57) | RAB9ASMN1; SMN2NPC1TP53CA1 | |
| SCHEMBL22290255 | 0.79 | NT5E (0.58) | ROCK2ROCK1RAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483496-B | Derivative with uracil-benzothiazole structure, preparation method thereof and application of anti-HCV (hepatitis C virus) medicament | 杭州市西溪医院 | 2021-05-04 | — | — | CN | disclosed |