Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3735176 | 0.83 | SRC (0.47) | SRCL3MBTL1TDP1CA12CA1 | |
| SCHEMBL21117276 | 0.83 | SRC (0.47) | SRCL3MBTL1TDP1CA12CA1 | |
| SCHEMBL28941447 | 0.81 | SRC (0.52) | SRCL3MBTL1TDP1KDM4ENPSR1 | |
| SCHEMBL9634847 | 0.78 | L3MBTL1 (0.50) | SRCL3MBTL1TDP1CA12CA1 | |
| SCHEMBL30164967 | 0.78 | L3MBTL1 (0.40) | L3MBTL1TDP1CA12CA1CA2 | |
| SCHEMBL31332475 | 0.77 | SRC (0.52) | SRCL3MBTL1TDP1KDM4ENPSR1 | |
| SCHEMBL23349551 | 0.76 | CYP3A4 (0.44) | SRCL3MBTL1TDP1CA12CA1 | |
| SCHEMBL29775299 | 0.76 | HCRTR1 (0.44) | SRCL3MBTL1TDP1KDM4ENPSR1 | |
| SCHEMBL21119420 | 0.74 | CYP3A4 (0.46) | SRCL3MBTL1TDP1CA12CA1 | |
| SCHEMBL20820172 | 0.73 | MEN1 (0.46) | SRCL3MBTL1TDP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778279-B | Preparation method of emedastine compound | 苏州正永生物医药有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-112778279-A | Preparation method of emedastine compound | 苏州正永生物医药有限公司 | 2021-05-11 | — | — | CN | disclosed |