Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 4/20 | 0.68 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28567341 | 0.90 | VEGFA (0.68) | VEGFAEGLN1KDM4EALDH1A1HTT | |
| SCHEMBL17005886 | 0.90 | VEGFA (0.54) | VEGFAEGLN1KDM4EALDH1A1HTT | |
| SCHEMBL28566297 | 0.90 | VEGFA (0.65) | VEGFAEGLN1KDM4EALDH1A1HTT | |
| SCHEMBL28563633 | 0.88 | VEGFA (0.71) | VEGFAEGLN1KDM4EALDH1A1HTT | |
| SCHEMBL17005965 | 0.88 | ALDH1A1 (0.52) | VEGFAEGLN1KDM4EALDH1A1HTT | |
| SCHEMBL28567992 | 0.87 | VEGFA (0.69) | VEGFAEGLN1KDM4EALDH1A1ALOX15 | |
| SCHEMBL28563005 | 0.87 | VEGFA (0.69) | VEGFAEGLN1KDM4EALDH1A1LMNA | |
| SCHEMBL28563641 | 0.87 | VEGFA (0.75) | VEGFAEGLN1KDM4EALDH1A1HTT | |
| SCHEMBL28571945 | 0.87 | VEGFA (0.69) | VEGFAEGLN1KDM4EALDH1A1POLB | |
| SCHEMBL17005930 | 0.87 | VEGFA (0.55) | VEGFAEGLN1KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | disclosed |