Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28410806 | 1.00 | NPC1 (0.39) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL28403240 | 0.92 | GAA (0.42) | BCHEKMT2AGAAABCB1PTGES2 | |
| SCHEMBL4261396 | 0.87 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL2505924 | 0.87 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL17560689 | 0.87 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL28499108 | 0.87 | BCHE (0.40) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL30336274 | 0.84 | NPC1 (0.38) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL28716091 | 0.83 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL28719208 | 0.81 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL30262558 | 0.81 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894576-B | Synthesis process of key intermediate of sofosbuvir | 江苏阿尔法药业股份有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-115894576-A | Synthesis process of Sofosbuvir key intermediate | 江苏阿尔法药业股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-113354700-B | Preparation method of sofosbuvir intermediate | 江苏阿尔法药业股份有限公司 | 2022-11-11 | — | — | CN | disclosed |