Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.64 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571047 | 0.88 | SLC22A12 (0.79) | NR4A2SLC22A12GAAL3MBTL1TSHR | |
| SCHEMBL28589203 | 0.85 | SLC22A12 (0.65) | NR4A2SLC22A12GAAL3MBTL1TSHR | |
| SCHEMBL28265757 | 0.84 | SLC22A12 (0.74) | SLC22A12L3MBTL1LMNAMAPTKDM4E | |
| SCHEMBL28915898 | 0.84 | SLC22A12 (0.61) | NR4A2SLC22A12GAATSHRLMNA | |
| SCHEMBL28915858 | 0.82 | CNR2 (0.61) | SLC22A12KDM4ECNR1CNR2 | |
| SCHEMBL28915861 | 0.82 | CNR2 (0.61) | SLC22A12KDM4ECNR1CNR2 | |
| SCHEMBL28584018 | 0.81 | SLC22A12 (0.58) | SLC22A12TSHRLMNAKDM4EPOLB | |
| SCHEMBL28155884 | 0.81 | SLC22A12 (0.60) | SLC22A12L3MBTL1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL5460505 | 0.81 | CNR1 (0.54) | NR4A2SLC22A12GAAL3MBTL1TSHR | |
| SCHEMBL2430574 | 0.80 | NR4A2 (0.72) | NR4A2GAAL3MBTL1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004188-B | Indole derivative, preparation method and application | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-113004188-A | Indole derivative, preparation method and application | 沈阳药科大学 | 2021-06-22 | — | — | CN | disclosed |