Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12642940 | 0.86 | CNR2 (0.71) | SLC22A12KDM4ECNR1CNR2LMNA | |
| SCHEMBL28589808 | 0.86 | SLC22A12 (1.00) | SLC22A12KDM4ECNR1CNR2LMNA | |
| SCHEMBL30547726 | 0.86 | KDM4E (0.62) | SLC22A12KDM4ECNR1CNR2LMNA | |
| SCHEMBL28155884 | 0.85 | SLC22A12 (0.60) | SLC22A12KDM4ECNR1CNR2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2038739 | 0.85 | CNR2 (0.69) | SLC22A12KDM4ECNR1CNR2ALDH1A1 | |
| SCHEMBL28914985 | 0.84 | NR4A2 (0.64) | SLC22A12KDM4ECNR1CNR2LMNA | |
| SCHEMBL28575851 | 0.84 | SLC22A12 (0.68) | SLC22A12KDM4ECNR1CNR2LMNA | |
| SCHEMBL30622546 | 0.83 | SLC22A12 (0.55) | SLC22A12KDM4ECNR1CNR2LMNA | |
| SCHEMBL28584451 | 0.82 | SLC22A12 (0.81) | SLC22A12KDM4ECNR1CNR2LMNA | |
| SCHEMBL28584456 | 0.82 | SLC22A12 (0.57) | SLC22A12KDM4ECNR1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004188-B | Indole derivative, preparation method and application | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-113004188-A | Indole derivative, preparation method and application | 沈阳药科大学 | 2021-06-22 | — | — | CN | disclosed |
| CN-109153643-A | Substituted indole MCL-1 inhibitors | 范德比尔特大学 | 2019-01-04 | — | — | CN | disclosed |