Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 4/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28915280 | 1.00 | TGM2 (0.51) | TGM2KMT2ATLR2MDM2MDM4 | |
| SCHEMBL25357181 | 0.87 | TGM2 (0.51) | TGM2KMT2ATLR2MDM2MDM4 | |
| SCHEMBL25357185 | 0.87 | TGM2 (0.51) | TGM2KMT2ATLR2MDM2MDM4 | |
| SCHEMBL25357858 | 0.87 | TGM2 (0.51) | TGM2KMT2ATLR2MDM2MDM4 | |
| SCHEMBL25358031 | 0.86 | KMT2A (0.51) | TGM2KMT2ATLR2MDM2MDM4 | |
| SCHEMBL12684664 | 0.86 | TGM2 (0.64) | TGM2KMT2A | |
| SCHEMBL25358036 | 0.86 | KMT2A (0.51) | TGM2KMT2ATLR2MDM2MDM4 | |
| SCHEMBL28582661 | 0.84 | TGM2 (0.68) | TGM2 | |
| SCHEMBL28582662 | 0.84 | TGM2 (0.68) | TGM2 | |
| SCHEMBL14360967 | 0.84 | KMT2A (0.45) | TGM2KMT2ATLR2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979491-B | Compound containing hydrogen peroxide/cathepsin L-responsive protective group and application thereof | 中国药科大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-112979491-A | Compound containing hydrogen peroxide/cathepsin L-responsive protective group and application thereof | 中国药科大学 | 2021-06-18 | — | — | CN | disclosed |