Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28915431 | 1.00 | OPRM1 (0.64) | OPRM1OPRK1OPRD1TP53SMN1; SMN2 | |
| SCHEMBL30072408 | 1.00 | OPRM1 (0.64) | OPRM1OPRK1OPRD1TP53SMN1; SMN2 | |
| SCHEMBL30072526 | 0.93 | OPRM1 (0.75) | OPRM1OPRK1OPRD1TP53SMN1; SMN2 | |
| SCHEMBL28915801 | 0.93 | OPRM1 (0.75) | OPRM1OPRK1OPRD1TP53SMN1; SMN2 | |
| SCHEMBL28915800 | 0.93 | OPRM1 (0.75) | OPRM1OPRK1OPRD1TP53SMN1; SMN2 | |
| SCHEMBL28915086 | 0.92 | OPRM1 (0.63) | OPRM1OPRK1OPRD1TP53SMN1; SMN2 | |
| SCHEMBL28915088 | 0.92 | OPRM1 (0.63) | OPRM1OPRK1OPRD1TP53SMN1; SMN2 | |
| SCHEMBL30072363 | 0.92 | OPRM1 (0.63) | OPRM1OPRK1OPRD1TP53SMN1; SMN2 | |
| SCHEMBL28961042 | 0.90 | OPRM1 (0.62) | OPRM1OPRK1OPRD1 | |
| SCHEMBL30072364 | 0.90 | OPRM1 (0.62) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115477634-B | Analgesic compounds and medical uses thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-02-13 | — | — | CN | disclosed |
| CN-115477634-A | Compound for analgesia and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-12-16 | — | — | CN | disclosed |