Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.67 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.67 |
| ▸ | F10 | P00742 | 6/20 | 0.48 |
| ▸ | F2 | P00734 | 6/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | F7 | P08709 | 2/20 | 0.46 |
| ▸ | F3 | P13726 | 2/20 | 0.46 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | C1S | P09871 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7370118 | 0.98 | CPN1 (0.65) | CPN1CPB2F10F2PRSS1 | |
| SCHEMBL9147869 | 0.82 | F10 (0.53) | CPN1CPB2F10F2PRSS1 | |
| SCHEMBL10957721 | 0.81 | GRM8 (0.44) | CPN1CPB2LMNACYP2C9CYP2C19 | |
| SCHEMBL4104203 | 0.80 | HSD17B10 (0.43) | CPN1CPB2F10PRSS1PRSS2 | |
| SCHEMBL22712583 | 0.80 | LMNA (0.42) | CPN1CPB2LMNACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL11656002 | 0.79 | CYP2C9 (0.46) | CPN1CPB2LMNACYP2C9CYP2C19 | |
| SCHEMBL21295020 | 0.79 | CPN1 (0.64) | CPN1CPB2 | |
| SCHEMBL4100564 | 0.79 | GAA (0.47) | CPN1CPB2LMNACYP2C9CYP2C19 | |
| SCHEMBL633268 | 0.78 | ESR1 (0.49) | LMNACYP2C9CYP2C19GAA | |
| SCHEMBL4269790 | 0.78 | POLB (0.51) | POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427476-A1 | BETA-HAIRPIN PEPTIDOMIMETICS HAVING CXCR4 ANTAGONIZING ACTIVITY | Polyphor Ag (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127704-A1 | BETA-HAIRPIN PEPTIDOMIMETICS HAVING CXCR4 ANTAGONIZING ACTIVITY | POLYPHOR AG (CH) | 2010-11-11 | — | — | WO | disclosed |
| US-5441974-A | Phenyl amidines lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-08-15 | — | — | US | disclosed |
| WO-1993012103-A1 | PHENYL AMIDINES LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | disclosed |