Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.39 |
| ▸ | TTK | P33981 | 4/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 7/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123228 | 0.90 | TTK (0.39) | ADORA3TTKPTK6LMNA | |
| Hydrochloric Acid SCHEMBL22123851 | 0.89 | TTK (0.39) | ADORA3TTKPTK6LMNA | |
| SCHEMBL28916220 | 0.88 | TTK (0.36) | TTKPTK6LMNAPOLB | |
| SCHEMBL22123531 | 0.88 | KDR (0.39) | ADORA3TTKPTK6PTK2 | |
| Hydrochloric Acid SCHEMBL25170259 | 0.87 | KDR (0.39) | ADORA3TTKPTK6PTK2 | |
| SCHEMBL25173410 | 0.87 | TTK (0.37) | TTKPTK6 | |
| SCHEMBL28961286 | 0.87 | PTK6 (0.47) | ADORA3TTKPTK6LMNAPOLB | |
| SCHEMBL28916262 | 0.86 | TTK (0.36) | TTKPTK6LMNA | |
| SCHEMBL22123829 | 0.84 | TTK (0.35) | TTKPTK6POLBMAP4K1 | |
| SCHEMBL22123737 | 0.83 | BRD4 (0.47) | ADORA3TTKPTK6IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115485279-A | Antibacterial 8-phenylamino-3- (pyrazol-4-yl) imidazo [1,2-a ] pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2022-12-16 | — | — | CN | disclosed |