Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 5/20 | 0.36 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123829 | 0.92 | TTK (0.35) | TTKKDRBRD4PTK6MAPT | |
| SCHEMBL25173410 | 0.90 | TTK (0.37) | TTKBRD4PTK6 | |
| SCHEMBL25241737 | 0.88 | BRD4 (0.46) | TTKBRD4PTK6KDM4EEGFR | |
| SCHEMBL28916220 | 0.88 | TTK (0.36) | TTKKDRBRD4PTK6MAPT | |
| Trifluoroacetic Acid SCHEMBL28982190 | 0.88 | SYK (0.34) | TTKKDRBRD4PTK6EGFR | |
| SCHEMBL28916287 | 0.86 | ADORA3 (0.39) | TTKPTK6LMNA | |
| SCHEMBL22123228 | 0.86 | TTK (0.39) | TTKBRD4PTK6KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL22123851 | 0.85 | TTK (0.39) | TTKBRD4PTK6KDM4ESMN1; SMN2 | |
| SCHEMBL22123737 | 0.84 | BRD4 (0.47) | TTKBRD4PTK6EGFR | |
| SCHEMBL28982191 | 0.84 | BRD4 (0.41) | TTKBRD4PTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115485279-A | Antibacterial 8-phenylamino-3- (pyrazol-4-yl) imidazo [1,2-a ] pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2022-12-16 | — | — | CN | disclosed |