Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 19/20 | 0.83 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30412509 | 0.91 | DHPS (1.00) | DHPS | |
| SCHEMBL28587118 | 0.91 | DHPS (1.00) | DHPS | |
| SCHEMBL28589605 | 0.88 | DHPS (0.82) | DHPS | |
| SCHEMBL7303389 | 0.88 | DHPS (0.81) | DHPS | |
| SCHEMBL28581580 | 0.87 | DHPS (0.82) | DHPS | |
| SCHEMBL28584053 | 0.87 | DHPS (0.82) | DHPS | |
| SCHEMBL7293762 | 0.87 | DHPS (0.82) | DHPSTP53SMN1; SMN2 | |
| SCHEMBL30450864 | 0.85 | DHPS (0.84) | DHPS | |
| SCHEMBL28589425 | 0.85 | DHPS (0.84) | DHPS | |
| SCHEMBL4071996 | 0.84 | DHPS (0.67) | DHPSNPC1TP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898208-B | Phenylpyrimidine amine antitumor compound and preparation method and application thereof | 中国医科大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-112898208-A | Phenyl pyrimidinamine antitumor compound and preparation method and application thereof | 中国医科大学 | 2021-06-04 | — | — | CN | disclosed |