Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21776941 | 1.00 | BTK (0.43) | BTKKCNH2TBK1LCK | |
| SCHEMBL21776943 | 0.88 | TBK1 (0.41) | BTKKCNH2TBK1 | |
| SCHEMBL21791276 | 0.88 | TBK1 (0.41) | BTKKCNH2TBK1 | |
| Hydrochloric Acid SCHEMBL28599177 | 0.87 | TBK1 (0.41) | BTKKCNH2TBK1 | |
| SCHEMBL28588591 | 0.84 | BTK (0.36) | BTK | |
| SCHEMBL21791274 | 0.83 | BTK (0.49) | BTKKCNH2TBK1 | |
| SCHEMBL24704293 | 0.80 | BTK (0.69) | BTKKCNH2 | |
| SCHEMBL21791275 | 0.80 | BTK (0.69) | BTKKCNH2LCK | |
| SCHEMBL21791283 | 0.80 | BTK (0.69) | BTKKCNH2LCK | |
| SCHEMBL24703842 | 0.80 | BTK (0.69) | BTKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112930213-A | Fused imidazopyridines as reversible inhibitors of Bruton's Tyrosine Kinase (BTK) | 默克专利有限公司 | 2021-06-08 | — | — | CN | disclosed |