Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28917623 | 0.99 | NPC1 (0.46) | NPC1HSP90AA1THRATHRBHDAC8 | |
| SCHEMBL28917703 | 0.91 | NPC1 (0.45) | NPC1HSP90AA1THRATHRBHDAC8 | |
| SCHEMBL28917886 | 0.90 | NR1H4 (0.45) | THRATHRBHDAC8HDAC6HDAC11 | |
| SCHEMBL28917704 | 0.89 | NR1H4 (0.44) | THRATHRBHDAC8HDAC6HDAC11 | |
| SCHEMBL28917636 | 0.89 | LMNA (0.47) | THRATHRBHDAC8HDAC6HDAC11 | |
| SCHEMBL28917647 | 0.88 | SMN1; SMN2 (0.41) | THRATHRBHDAC8HDAC6HDAC11 | |
| SCHEMBL28917692 | 0.88 | LMNA (0.47) | THRATHRBHDAC8HDAC6HDAC11 | |
| SCHEMBL28917646 | 0.87 | SMN1; SMN2 (0.43) | THRATHRBHDAC8HDAC6HDAC11 | |
| SCHEMBL28961411 | 0.82 | SMN1; SMN2 (0.44) | THRATHRBHDAC8HDAC6HDAC11 | |
| SCHEMBL28917885 | 0.81 | HTR2C (0.45) | THRATHRBHDAC8HDAC6HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229091-B | 1, 5-disubstituted indole derivatives with leukotriene A4 hydrolase inhibition effect and application thereof | 天津科技大学 | 2022-11-22 | — | — | CN | disclosed |