Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.30 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.30 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15650507 | 0.83 | KDM5A (0.44) | KDM5AFGFR1FGFR2FGFR3DRD4 | |
| SCHEMBL15651751 | 0.78 | DYRK1A (0.41) | KDM5AACHEFGFR1FGFR2FGFR3 | |
| SCHEMBL28918285 | 0.78 | DRD4 (0.36) | ACHEFGFR1FGFR2FGFR3DRD4 | |
| SCHEMBL22648410 | 0.78 | KDM5A (0.41) | KDM5AACHEDRD4SIGMAR1MET | |
| SCHEMBL17076783 | 0.77 | FGFR1 (0.42) | KDM5AACHEFGFR1FGFR2FGFR3 | |
| SCHEMBL22648374 | 0.77 | MET (0.38) | KDM5AACHEDRD4SIGMAR1MET | |
| SCHEMBL10191753 | 0.75 | BTK (0.41) | KDM5AACHEDRD4METDYRK1A | |
| SCHEMBL23612181 | 0.75 | GSK3B (0.45) | KDM5AACHEFGFR1FGFR2FGFR3 | |
| SCHEMBL173506 | 0.75 | — | — | |
| SCHEMBL13734972 | 0.74 | JAK1 (0.43) | KDM5AACHEDRD4SIGMAR1MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115348957-A | Compounds and compositions for treating diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2022-11-15 | — | — | CN | disclosed |