SCHEMBL28918804

SCHEMBL28918804

CCCOc1c(-c2ccccc2F)ccc(C2(C=O)CCCCC2)c1F

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.32
SLC6A4 P31645 3/20 0.32
SLC6A3 Q01959 3/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PARP1 P09874 1/20 0.32
PARP2 Q9UGN5 1/20 0.32
CTSL P07711 2/20 0.32
CTSS P25774 2/20 0.32
CTSK P43235 2/20 0.32
USP19 O94966 2/20 0.31
FFAR4 Q5NUL3 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28918799 0.94 PDK2 (0.34) PDK2SLC6A4SLC6A3ALDH1A1PARP1
SCHEMBL28918791 0.92 PARP1 (0.34) SLC6A4SLC6A3ALDH1A1PARP1PARP2
SCHEMBL28918811 0.89 PARP1 (0.34) SLC6A4SLC6A3ALDH1A1HSD17B10PARP1
SCHEMBL28918802 0.74 FFAR4 (0.40) PARP1PARP2FFAR4
SCHEMBL11894870 0.72 ALDH1A1 (0.33) ALDH1A1CTSLCTSSCTSK
SCHEMBL1243389 0.71 ALDH1A1 (0.36) SLC6A4SLC6A3ALDH1A1HSD17B10TSHR
SCHEMBL28918797 0.70 FFAR4 (0.38) PARP1PARP2FFAR4
SCHEMBL28918787 0.67 FGFR1 (0.44) PDK2ALDH1A1PARP1PARP2FFAR4
SCHEMBL19357510 0.66 HDAC4 (0.40) PDK2MAPK1
SCHEMBL5637544 0.65 HDAC4 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115490582-B Preparation method of fluorine-containing biphenyl alkene negative monomer liquid crystal compound 烟台德润液晶材料有限公司 2023-10-10 CN disclosed
CN-115490582-A Preparation method of fluorine-containing biphenyl alkene negative monomer liquid crystal compound 烟台德润液晶材料有限公司 2022-12-20 CN disclosed