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Acetophenone

Acetophenone

SCHEMBL28919004

CC(=O)c1ccccc1.c1cc[nH]c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 4/20 0.56
▸ MAPT P10636 3/20 0.56
▸ LMNA P02545 1/20 0.55
▸ HPGD P15428 3/20 0.50
▸ ALDH1A1 P00352 3/20 0.50
▸ CES1 P23141 4/20 0.48
▸ CES2 O00748 3/20 0.48
▸ MAOB P27338 2/20 0.47
▸ NPC1 O15118 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ TAAR1 Q96RJ0 1/20 0.47
▸ KMT2A Q03164 3/20 0.46
▸ HTT P42858 2/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ MEN1 O00255 2/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetophenone SCHEMBL27977927 0.98 SMN1; SMN2 (0.54) SMN1; SMN2MAPTLMNAHPGDALDH1A1
Acetophenone SCHEMBL719033 0.85 MAPT (0.71) SMN1; SMN2MAPTLMNAHPGDALDH1A1
Acetophenone SCHEMBL16745259 0.85 — —
Acetophenone SCHEMBL30537005 0.85 — —
Acetophenone SCHEMBL1450855 0.85 — —
Acetophenone SCHEMBL27462873 0.85 MAPT (0.71) SMN1; SMN2MAPTLMNAHPGDALDH1A1
Acetophenone SCHEMBL737 0.85 — —
Acetophenone SCHEMBL30537000 0.85 — —
Acetophenone SCHEMBL6573416 0.83 MAPT (0.68) SMN1; SMN2MAPTLMNAHPGDALDH1A1
Acetophenone SCHEMBL12475398 0.83 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115521258-B Alpha-alkoxyl azole acetophenone derivatives and synthesis method thereof 浙江树人学院 2024-04-30 — — CN claimed
CN-115521257-B Alpha-substituted azole acetophenone derivatives and synthesis method thereof 浙江树人学院 2024-04-30 — — CN claimed
CN-115521257-A Alpha-substituted azolidone derivative and synthesis method thereof 浙江树人学院 2022-12-27 — — CN claimed
CN-115521258-A Alpha-alkoxy azole acetophenone derivatives and synthesis method thereof 浙江树人学院 2022-12-27 — — CN claimed
CN-118726999-A Preparation method of phosphoryl azole acetophenone derivatives 上海兆维科技发展有限公司 2024-10-01 — — CN disclosed
CN-115521258-B Alpha-alkoxyl azole acetophenone derivatives and synthesis method thereof 浙江树人学院 2024-04-30 — — CN disclosed
CN-115521258-B Alpha-alkoxyl azole acetophenone derivatives and synthesis method thereof 浙江树人学院 2024-04-30 — — CN disclosed
CN-115521258-B Alpha-alkoxyl azole acetophenone derivatives and synthesis method thereof 浙江树人学院 2024-04-30 — — CN disclosed
CN-115521257-B Alpha-substituted azole acetophenone derivatives and synthesis method thereof 浙江树人学院 2024-04-30 — — CN disclosed
CN-115521257-B Alpha-substituted azole acetophenone derivatives and synthesis method thereof 浙江树人学院 2024-04-30 — — CN disclosed
CN-115521257-B Alpha-substituted azole acetophenone derivatives and synthesis method thereof 浙江树人学院 2024-04-30 — — CN disclosed
CN-115521258-A Alpha-alkoxy azole acetophenone derivatives and synthesis method thereof 浙江树人学院 2022-12-27 — — CN disclosed
CN-115521257-A Alpha-substituted azolidone derivative and synthesis method thereof 浙江树人学院 2022-12-27 — — CN disclosed
CN-115521258-A Alpha-alkoxy azole acetophenone derivatives and synthesis method thereof 浙江树人学院 2022-12-27 — — CN disclosed
CN-115521258-A Alpha-alkoxy azole acetophenone derivatives and synthesis method thereof 浙江树人学院 2022-12-27 — — CN disclosed
CN-115521257-A Alpha-substituted azolidone derivative and synthesis method thereof 浙江树人学院 2022-12-27 — — CN disclosed
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