Acetophenone

Acetophenone

SCHEMBL719033

CC(=O)c1ccccc1.CC(=O)c1ccccc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.71
SMN1; SMN2 Q16637 2/20 0.71
HPGD P15428 4/20 0.62
ALDH1A1 P00352 2/20 0.62
LMNA P02545 2/20 0.62
CES2 O00748 4/20 0.62
CES1 P23141 4/20 0.62
TSHR P16473 3/20 0.58
DAO P14920 1/20 0.58
NAPRT Q6XQN6 1/20 0.58
RAB9A P51151 2/20 0.58
NPC1 O15118 1/20 0.58
TAAR1 Q96RJ0 1/20 0.58
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.52
POLB P06746 1/20 0.52
CYP3A4 P08684 1/20 0.52
PARP1 P09874 1/20 0.52
CYP2C19 P33261 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetophenone SCHEMBL1450855 1.00
Acetophenone SCHEMBL30537000 1.00
Acetophenone SCHEMBL27462873 1.00 MAPT (0.71) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Acetophenone SCHEMBL737 1.00
Acetophenone SCHEMBL30537005 1.00
Acetophenone SCHEMBL16745259 1.00
Acetophenone SCHEMBL11876785 0.97 MAPT (0.68) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Acetophenone SCHEMBL11354178 0.97 MAPT (0.68) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Acetophenone SCHEMBL1404141 0.97 MAPT (0.68) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Acetophenone SCHEMBL4356164 0.97 MAPT (0.68) MAPTSMN1; SMN2HPGDALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108373658-A LED-UV piezoelectric type ink-jet inks of high adhesion force and preparation method thereof 大丰鑫源达化工有限公司 2018-08-07 CN claimed
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
CN-109761777-A Acetophenone preparation method and system 江西华尔盛科贸有限公司 2019-05-17 CN disclosed
US-20180253534-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-09-06 US disclosed
CN-108373658-A LED-UV piezoelectric type ink-jet inks of high adhesion force and preparation method thereof 大丰鑫源达化工有限公司 2018-08-07 CN disclosed
CN-108210422-A A kind of natural anti-apolexis composition and its application 佛山娇芙生物科技有限公司 2018-06-29 CN disclosed
WO-2018037361-A1 MITICIDAL, INSECTICIDAL AND NEMATOCIDAL COMPOSITIONS CONTAINING PLANTS EXTRACTS FROM BULNESIA SP AND HUMULUS SP ECOFLORA AGRO SAS (CO) 2018-03-01 WO disclosed
EP-3204457-A1 POLYETHERIMIDE VARNISH COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM SABIC Global Technologies B.V. (NL) 2017-08-16 EP disclosed
WO-2017008903-A1 ODORLESS POLYESTER STABILIZER COMPOSITIONS HEXION RESEARCH BELGIUM SA (BE) 2017-01-19 WO disclosed
WO-2016055926-A1 POLYETHERIMIDE VARNISH COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-04-14 WO disclosed
CN-101421213-A Method for treating phenol INEOS PHENOL GMBH & CO KG (DE) 2009-04-29 CN disclosed
CN-101421212-A Process for removal of hydroxyacetone from phenol INEOS PHENOL GMBH & CO KG (DE) 2009-04-29 CN disclosed
EP-1894603-A1 Encapsulation of bulky fragrance molecules Takasago International Corporation (JP) 2008-03-05 EP disclosed
US-20080032912-A1 Use of fragrance compositions for the prevention of the development of indole base malodours from fecal and urine based soils TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-02-07 US disclosed
EP-1884251-A1 Use of fragrance compositions for the prevention of the development of indole based malodours from faecal and urine based soils Takasago International Corporation (JP) 2008-02-06 EP disclosed
US-20070141011-A1 USE OF DYNAMIC MIXTURES FOR A CONTROLLED RELEASE OF FRAGRANCES UNIVERSITE LOUIS PASTEUR (FR) 2007-06-21 US disclosed
CN-1890198-A Process for preparing styrene SHELL INT RESEARCH (NL) 2007-01-03 CN disclosed
EP-0477983-B1 Unsaturated polylactone acrylates and derivatives thereof UNION CARBIDE CHEM PLASTIC (US) 1996-11-13 EP disclosed
US-5557007-A Unsaturated polylactone acrylates and derivatives thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-09-17 US disclosed
EP-0477983-A2 Unsaturated polylactone acrylates and derivatives thereof UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070141011-A1 USE OF DYNAMIC MIXTURES FOR A CONTROLLED RELEASE OF FRAGRANCES TRPA1, HCN1, HCN4 MAPT 1790/4885SMN1; SMN2 3248/4885HPGD 133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.