Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22679867 | 1.00 | KDM4E (0.53) | KDM4EHRH3JAK2JAK3KMT2A | |
| SCHEMBL22655502 | 0.84 | NOTUM (0.57) | KDM4EHRH3NOTUM | |
| SCHEMBL21994305 | 0.84 | NOTUM (0.57) | KDM4EHRH3NOTUM | |
| SCHEMBL16695451 | 0.81 | KDM4E (0.56) | KDM4EHRH3JAK2JAK3KMT2A | |
| SCHEMBL22680304 | 0.78 | KDM4E (0.48) | KDM4EJAK2JAK3KMT2AMEN1 | |
| SCHEMBL29429480 | 0.78 | KDM4E (0.48) | KDM4EJAK2JAK3KMT2AMEN1 | |
| SCHEMBL28601851 | 0.78 | KDM4E (0.48) | KDM4EJAK2JAK3KMT2AMEN1 | |
| SCHEMBL25245322 | 0.78 | KDM4E (0.64) | KDM4EHRH3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL22533443 | 0.78 | KDM4E (0.64) | KDM4EKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL23582281 | 0.78 | LMNA (0.55) | KDM4EHRH3JAK2JAK3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166146-A | Other heteroaromatic compounds with anti-RSV activity | 爱尔兰詹森科学公司 | 2021-07-23 | — | — | CN | disclosed |